Friday, August 3, 2018
New report | Global Blood-Brain Barrier Market | Analysis and Forecast to 2026
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According to the latest report published by Credence Research, Inc.
“Blood-Brain Barrier Market - Growth, Future Prospects and Competitive
Analysis, 2018-2026,” the blood-brain barrier market was valued at USD 496.4 Mn
in 2016, and is expected to reach USD 5,704.2 Mn by 2026, expanding at a CAGR
of 25.0% from 2018 to 2026.
Market
Insights
The blood-brain barrier (BBB) plays important role in protecting the
brain from toxic compounds and blood-borne disorders. Thus, in the case of
central nervous system diseases, it is vital to get treatments across this
barrier and deliver desired effect at the targeted location. According to
experts, more than 98% of small molecules drugs and nearly 100% of larger
biologic drugs cannot enter the brain at adequate concentrations to project
therapeutic effects. The three main BBB permeation mechanisms that occur are
passive diffusion, endocytosis, and active transport. Passive diffusion occurs
by two mechanisms free and facilitated, endocytosis occurs by bulk phase and
facilitated, and active transport through influx and efflux.
Browse the
full report Blood-Brain Barrier Market - Growth, Future Prospects and
Competitive Analysis, 2018-2026 report at http://www.credenceresearch.com/report/blood-brain-barrier-market
Technological development has introduced several key approaches for brain
targeting include transport mechanisms such as cell-mediated endocytosis, the
reticence of active efflux pumps, adsorptive-mediated transcytosis,
receptor-mediated transport, and the use of peptide vectors. Drug delivery
technologies comprise delivery with the assistance of liposomes, nanoparticles,
nanogels, dendrimers, nanoemulsions, micelles, exosomes, polymersomes, and
quantum dots.
According to market experts, increasing prevalence of neurological
diseases, growing geriatric population, rising healthcare expenditure, mounting
investment in pharmaceutical research and development, high awareness associated
with chronic neurological diseases, and supportive policies and awareness
campaigns organized by government organizations are observed as the key driving
factors for significant growth of blood-brain barrier market.
By technology blood-brain barrier market is segmented as bispecific
antibody RMT approach, Trojan Horse approach, increasing the permeability of
BBB, passive diffusion, and other non-invasive BBB technologies. In the year
2016, Trojan Horse approach was observed as the largest segment in BBB market
due to key factors such as the ability to deliver bispecific antibodies to the
brain at therapeutic doses and its high membrane permeability. However,
bispecific antibody RMT approach is expected to be the fastest growing segment
due to the entry of novel BBB technologies such as Ossianix Blood-Brain Barrier
Technology (Ossianix) and Brain Shuttle Technology (Roche). Rising application
of these two technologies in brain tumor treatment is expected to boost the
overall growth of the segment throughout the forecast period 2018 - 2026.
On the basis of diseases, blood-brain barrier market was segmented as
Alzheimer’s disease, Epilepsy, Parkinson’s disease, multiple sclerosis,
Hunter’s syndrome, and Brain Cancer. In 2016, the BBB market was dominated by
Alzheimer’s and Parkinson’s disease with more than 50% of the market share
collectively owing to peaking prevalence of these diseases, introduction of
technologically upgraded diagnostic technology for neurological diseases, and
increasing awareness programs organized by non-governmental and governmental
organizations. According to World Health Organization (WHO), around 50 million
people globally have epilepsy, which makes it one of the most common
neurological diseases globally and approximately 80% of the people with
epilepsy live in low- and middle-income countries. Thus, incessant
technological developments in the field of BBB is expected to assist the market
growth throughout the forecast period 2018 – 2026.
Market
Competition Assessment:
The blood-brain barrier market is the most competitive market comprising
a large number of players with a wide range of products and ongoing research
and developments studies. The key players in this market are F. Hoffmann
La-Roche, Ltd., Ossianix, Inc., Eli Lilly And Company, Bristol-Myers Squibb
Company, Sanofi Genzyme, biOasia Technologies, Inc., Envivo Pharmaceuticals,
Inc., Sagetis Biotech, Janssen Pharmaceutica NV, and ArmaGen among others.
Key
Market Movements:
• Rising prevalence of
neurological diseases coupled with a rising in treatment limitations associated
with blood-brain barrier
• Incessant growth in research
and development activities carried out in BBB technologies market
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Browse
the full report Blood-Brain Barrier Market - Growth, Future Prospects and
Competitive Analysis, 2018-2026 report at http://www.credenceresearch.com/report/blood-brain-barrier-market
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